Typhoid vaccine can prevent typhoid fever. People who are actively ill with typhoid fever and people who are carriers of the bacteria that cause typhoid fever can both spread the bacteria to others. When someone eats or drinks contaminated food or drink, the bacteria can multiply and spread into the bloodstream, causing typhoid fever.Typhoid fever can be a life-threatening disease. Symptoms of infection include persistent high fever, weakness, stomach pain, headache, diarrhea or constipation, cough, and loss of appetite.

Frequency of shots:
The immunizing dose for adults and children is a single injection of 0.5 mL. A reimmunizing dose is 0.5 mL.

Who can use this:
This is approved for use in persons two years of age or older.
Selective immunization against typhoid fever is recommended under the following circumstances:
1) travelers to areas where a recognized risk of exposure to typhoid exists, particularly ones who will have prolonged exposure to potentially contaminated food and water
2) persons with intimate exposure (ie, continued household contact) to a documented typhoid carrier
3) workers in microbiology laboratories who frequently work with S typhi.

Who CANNOT use this:
- Has had an allergic reaction after a previous dose of typhoid vaccine, or has any severe, life-threatening allergies.
- Has a weakened immune system.
- Is pregnant or breastfeeding, or thinks she might be pregnant.
- Is taking or has recently taken antibiotics or anti-malarial drugs.